substantianigra相关论文
Nifedipine reduces iron accumulation and dopamine neuron degeneration in the iron-overloaded substan
Objective To investigate whether nifedipine, a blocker of L-type calcium channels can prevent iron accumulation and dopa......
Neuro-immune crosstalk connects the nervous and immune systems.Pathogenesis of nervous system diseases are related to in......
Lesion of the locus ceruleus aggravates dopaminergic neuron injury by modulating microglial function
Parkinsons disease (PD) is considered to have selective cell loss of dopaminergic neurons in the substantia nigra (SN).I......
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To investigate the neuroprotective effects of LK001 in a nonhuman primate model of Parkinsons disease induced by 1-Methy......
目的评价丙泊酚对帕金森病(PD)小鼠黑质炎症反应的影响及其与α-突触核蛋白(α-syn)表达的关系。方法SPF级健康雄性C57BL/6小鼠33......
Neuronal quantity and ultrastructure in extracorticospinal tract of newborn rabbits with cerebral pa
BACKGROUND: The liver enzyme system and blood brain barrier function of newb rabbits are incomplete.High level of biliru......
BACKGROUND: Insulin receptor (IR) expression in the substantia nigra of patients with Parkinson disease (PD) is not only......
Mechanisms of secondary damage to the thalamic nucleus and substantia nigra in an adult hypertensive
BACKGROUND: Following ischemia, apoptosis is observed at the ipsilateral ventroposterior thalamic nucleus and substantia......
Anti-apoptotic effect ofShudipingchan granule in the substantia nigra of rat models of Parkinson’s d
Levodopa is the gold-standard treatment for Parkinson’s disease. However, although it alleviates the clinical symptoms,......
We previously reported that intranasal insulin protects substantia nigra dopaminergic neurons against6-hydroxydopamine n......
Background: Parkinson s disease (PD) is a degeneration disease with the main lesion being in the substantia nigra and co......
BACKGROUND: Cellular adhesion molecule mediates the effects of glial cell line-derived neurotrophic factor in dopaminerg......
目的观察大鼠帕金森综合征模型脑内黑质、尾状核及中缝核神经元超微结构变化,为阐述该病的发病机制及筛选有效药物,提供实验依据.......
目的 观察脑室内注射脂多糖(lipopolysaccharide,LPS)引起的脑内炎症对大鼠黑质多巴胺能神经元的慢性毒性作用,探讨星形胶质细胞是......
Differential protein expression in substantia nigra induced by 1-methyl-4-phenyl-1, 2, 3, 6-tetrahyd
BACKGROUND: To date, a complete protein expression profile of the midbrain substantia nigra in a mouse model of chronic ......
